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Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database

BACKGROUND: Clear cell sarcoma (CCS) of soft tissue, or malignant melanoma of soft parts, is a rare disease. We aimed to identify prognostic factors linked to patient survival in CCS by analyzing demographic and clinical features using the Surveillance, Epidemiology, and End Results (SEER) database....

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Autores principales: Li, A-Bing, Jiang, Bing-Jie, Wang, He-Hui, Yang, Yu-Sheng, Zhang, Xiao-Bo, Lan, Guan-Hua, Shu, Wu-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761855/
https://www.ncbi.nlm.nih.gov/pubmed/31522190
http://dx.doi.org/10.12659/MSM.916705
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author Li, A-Bing
Jiang, Bing-Jie
Wang, He-Hui
Yang, Yu-Sheng
Zhang, Xiao-Bo
Lan, Guan-Hua
Shu, Wu-Bin
author_facet Li, A-Bing
Jiang, Bing-Jie
Wang, He-Hui
Yang, Yu-Sheng
Zhang, Xiao-Bo
Lan, Guan-Hua
Shu, Wu-Bin
author_sort Li, A-Bing
collection PubMed
description BACKGROUND: Clear cell sarcoma (CCS) of soft tissue, or malignant melanoma of soft parts, is a rare disease. We aimed to identify prognostic factors linked to patient survival in CCS by analyzing demographic and clinical features using the Surveillance, Epidemiology, and End Results (SEER) database. This study aimed to identify prognostic factors associated with CCS that would be of clinical value. MATERIAL/METHODS: We collected data from patients diagnosed with CCS between 1973 and 2009 from the SEER database. The Kaplan-Meier method and Cox regression analysis were performed to identify prognostic factors for patient survival. RESULTS: A total of 175 patients with CCS were identified from the SEER database. The 5-year survival rate was 62.9%, and the 10-year survival rate was 51.3%. Patients with CCS with local stage, and with tumor size ≤3 cm were more likely to have good survival rates. CONCLUSIONS: The findings from this study showed that the identifiable prognostic factors in patients with CCS were stage and tumor size. Local stage and tumor size ≤3 cm were favorable prognostic factors for patient survival in CCS.
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spelling pubmed-67618552019-10-02 Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database Li, A-Bing Jiang, Bing-Jie Wang, He-Hui Yang, Yu-Sheng Zhang, Xiao-Bo Lan, Guan-Hua Shu, Wu-Bin Med Sci Monit Clinical Research BACKGROUND: Clear cell sarcoma (CCS) of soft tissue, or malignant melanoma of soft parts, is a rare disease. We aimed to identify prognostic factors linked to patient survival in CCS by analyzing demographic and clinical features using the Surveillance, Epidemiology, and End Results (SEER) database. This study aimed to identify prognostic factors associated with CCS that would be of clinical value. MATERIAL/METHODS: We collected data from patients diagnosed with CCS between 1973 and 2009 from the SEER database. The Kaplan-Meier method and Cox regression analysis were performed to identify prognostic factors for patient survival. RESULTS: A total of 175 patients with CCS were identified from the SEER database. The 5-year survival rate was 62.9%, and the 10-year survival rate was 51.3%. Patients with CCS with local stage, and with tumor size ≤3 cm were more likely to have good survival rates. CONCLUSIONS: The findings from this study showed that the identifiable prognostic factors in patients with CCS were stage and tumor size. Local stage and tumor size ≤3 cm were favorable prognostic factors for patient survival in CCS. International Scientific Literature, Inc. 2019-09-15 /pmc/articles/PMC6761855/ /pubmed/31522190 http://dx.doi.org/10.12659/MSM.916705 Text en © Med Sci Monit, 2019 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Li, A-Bing
Jiang, Bing-Jie
Wang, He-Hui
Yang, Yu-Sheng
Zhang, Xiao-Bo
Lan, Guan-Hua
Shu, Wu-Bin
Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
title Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
title_full Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
title_fullStr Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
title_full_unstemmed Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
title_short Prognostic Factors for Survival in Patients with Clear Cell Sarcoma: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database
title_sort prognostic factors for survival in patients with clear cell sarcoma: an analysis of the surveillance, epidemiology, and end results (seer) database
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761855/
https://www.ncbi.nlm.nih.gov/pubmed/31522190
http://dx.doi.org/10.12659/MSM.916705
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