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RECAP reveals the true statistical significance of ChIP-seq peak calls

MOTIVATION: Chromatin Immunopreciptation (ChIP)-seq is used extensively to identify sites of transcription factor binding or regions of epigenetic modifications to the genome. A key step in ChIP-seq analysis is peak calling, where genomic regions enriched for ChIP versus control reads are identified...

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Detalles Bibliográficos
Autores principales:	Chitpin, Justin G, Awdeh, Aseel, Perkins, Theodore J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761936/ https://www.ncbi.nlm.nih.gov/pubmed/30824903 http://dx.doi.org/10.1093/bioinformatics/btz150

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