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Dr.VAE: improving drug response prediction via modeling of drug perturbation effects

MOTIVATION: Individualized drug response prediction is a fundamental part of personalized medicine for cancer. Great effort has been made to discover biomarkers or to develop machine learning methods for accurate drug response prediction in cancers. Incorporating prior knowledge of biological system...

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Detalles Bibliográficos
Autores principales:	Rampášek, Ladislav, Hidru, Daniel, Smirnov, Petr, Haibe-Kains, Benjamin, Goldenberg, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761940/ https://www.ncbi.nlm.nih.gov/pubmed/30850846 http://dx.doi.org/10.1093/bioinformatics/btz158

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