mirtronDB: a mirtron knowledge base

MOTIVATION: Mirtrons arise from short introns with atypical cleavage by using the splicing mechanism. In the current literature, there is no repository centralizing and organizing the data available to the public. To fill this gap, we developed mirtronDB, the first knowledge database dedicated to mi...

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Detalles Bibliográficos
Autores principales: Da Fonseca, Bruno Henrique Ribeiro, Domingues, Douglas Silva, Paschoal, Alexandre Rossi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761972/
https://www.ncbi.nlm.nih.gov/pubmed/30874795
http://dx.doi.org/10.1093/bioinformatics/btz153
Descripción
Sumario:MOTIVATION: Mirtrons arise from short introns with atypical cleavage by using the splicing mechanism. In the current literature, there is no repository centralizing and organizing the data available to the public. To fill this gap, we developed mirtronDB, the first knowledge database dedicated to mirtron, and it is available at http://mirtrondb.cp.utfpr.edu.br/. MirtronDB currently contains a total of 1407 mirtron precursors and 2426 mirtron mature sequences in 18 species. RESULTS: Through a user-friendly interface, users can now browse and search mirtrons by organism, organism group, type and name. MirtronDB is a specialized resource that provides free and user-friendly access to knowledge on mirtron data. AVAILABILITY AND IMPLEMENTATION: MirtronDB is available at http://mirtrondb.cp.utfpr.edu.br/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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