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Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection
BACKGROUND: Candidalysin is a cytolytic peptide toxin secreted by Candida albicans hyphae and has significantly advanced our understanding of fungal pathogenesis. Candidalysin is critical for mucosal C albicans infections and is known to activate epithelial cells to induce downstream innate immune r...
Autores principales: | Swidergall, Marc, Khalaji, Mina, Solis, Norma V, Moyes, David L, Drummond, Rebecca A, Hube, Bernhard, Lionakis, Michail S, Murdoch, Craig, Filler, Scott G, Naglik, Julian R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761979/ https://www.ncbi.nlm.nih.gov/pubmed/31401652 http://dx.doi.org/10.1093/infdis/jiz322 |
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