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Antitumor activity of a novel dual functional podophyllotoxin derivative involved PI3K/AKT/mTOR pathway

The progression of cancer through local expansion and metastasis is well recognized, but preventing these characteristic cancer processes is challenging. To this end, a new strategy is required. In this study, we presented a novel dual functional podophyllotoxin derivative, 2-pyridinealdehyde hydraz...

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Detalles Bibliográficos
Autores principales: Li, Yongli, Huang, Tengfei, Fu, Yun, Wang, Tingting, Zhao, Tiesuo, Guo, Sheng, Sun, Yanjie, Yang, Yun, Li, Changzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763125/
https://www.ncbi.nlm.nih.gov/pubmed/31557166
http://dx.doi.org/10.1371/journal.pone.0215886