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Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge
Cytomegalovirus (CMV) is a ubiquitous β-herpesvirus that establishes life-long latent infection in a high percentage of the population worldwide. CMV induces the strongest and most durable CD8(+) T cell response known in human clinical medicine. Due to its unique properties, the virus represents a p...
Autores principales: | Zheng, Xiaoyan, Oduro, Jennifer D., Boehme, Julia D., Borkner, Lisa, Ebensen, Thomas, Heise, Ulrike, Gereke, Marcus, Pils, Marina C., Krmpotic, Astrid, Guzmán, Carlos A., Bruder, Dunja, Čičin-Šain, Luka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763260/ https://www.ncbi.nlm.nih.gov/pubmed/31525249 http://dx.doi.org/10.1371/journal.ppat.1008036 |
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