Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca(2+)

The endoplasmic reticulum (ER) imports ATP and uses energy from ATP hydrolysis for protein folding and trafficking. However, little is known about how this vital ATP transport occurs across the ER membrane. Here, using three commonly used cell lines (CHO, INS1 and HeLa), we report that ATP enters th...

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Detalles Bibliográficos
Autores principales: Yong, Jing, Bischof, Helmut, Burgstaller, Sandra, Siirin, Marina, Murphy, Anne, Malli, Roland, Kaufman, Randal J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763289/
https://www.ncbi.nlm.nih.gov/pubmed/31498082
http://dx.doi.org/10.7554/eLife.49682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763289/
https://www.ncbi.nlm.nih.gov/pubmed/31498082
http://dx.doi.org/10.7554/eLife.49682

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