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Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca(2+)
The endoplasmic reticulum (ER) imports ATP and uses energy from ATP hydrolysis for protein folding and trafficking. However, little is known about how this vital ATP transport occurs across the ER membrane. Here, using three commonly used cell lines (CHO, INS1 and HeLa), we report that ATP enters th...
Autores principales: | Yong, Jing, Bischof, Helmut, Burgstaller, Sandra, Siirin, Marina, Murphy, Anne, Malli, Roland, Kaufman, Randal J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763289/ https://www.ncbi.nlm.nih.gov/pubmed/31498082 http://dx.doi.org/10.7554/eLife.49682 |
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