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eIF5B gates the transition from translation initiation to elongation

Translation initiation determines both the quantity and identity of the protein encoded in an mRNA by establishing the reading frame for protein synthesis. In eukaryotic cells, numerous translation initiation factors (eIFs) prepare ribosomes for polypeptide synthesis, yet the underlying dynamics of...

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Detalles Bibliográficos
Autores principales:	Wang, Jinfan, Johnson, Alex G., Lapointe, Christopher P., Choi, Junhong, Prabhakar, Arjun, Chen, Dong-Hua, Petrov, Alexey N., Puglisi, Joseph D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763361/ https://www.ncbi.nlm.nih.gov/pubmed/31534220 http://dx.doi.org/10.1038/s41586-019-1561-0

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