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microRNA-17 functions as an oncogene by downregulating Smad3 expression in hepatocellular carcinoma

The sekelsky mothers against dpp3 (Smad3) functions as a transcriptional modulator activated by transforming growth factor-β (TGF-β). Accumulated evidences indicated that Smad3 played the important roles in carcinogenesis and progression of hepatocellular carcinoma (HCC). Up to now, the regulatory m...

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Detalles Bibliográficos
Autores principales: Lu, Zhufeng, Li, Xiuhua, Xu, Yongfeng, Chen, Miaomiao, Chen, Wei, Chen, Tao, Tang, Qinghe, He, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763424/
https://www.ncbi.nlm.nih.gov/pubmed/31558704
http://dx.doi.org/10.1038/s41419-019-1960-z