Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma

The ubiquitin–proteasome system (UPS) is a tight homeostatic control mechanism of intracellular protein degradation and turnover involved in many human diseases. Proteasome inhibitors were initially developed as anticancer agents with potential benefits in the suppression of tumor growth. However, c...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaolan, Lin, Chun, Song, Junwei, Chen, Han, Chen, Xuhong, Ren, Liangliang, Zhou, Zhongqiu, Pan, Jinyuan, Yang, Zhenjun, Bao, Wenhao, Ke, Xueping, Yang, Jianan, Liang, Yingying, Huang, Hongbiao, Tang, Daolin, Jiang, Lili, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763437/
https://www.ncbi.nlm.nih.gov/pubmed/31558697
http://dx.doi.org/10.1038/s41419-019-1881-x

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