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Dedifferentiation process driven by radiotherapy-induced HMGB1/TLR2/YAP/HIF-1α signaling enhances pancreatic cancer stemness

Differentiated cancer cells reacquiring stem cell traits following radiotherapy may enrich cancer stem cells and accelerate tumor recurrence and metastasis. We are interested in the mechanistic role of dying cells-derived HMGB1 in CD133(−) pancreatic cancer cells dedifferentiation following radiothe...

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Detalles Bibliográficos
Autores principales:	Zhang, Lirong, Shi, Hui, Chen, Hongbo, Gong, Aihua, Liu, Yanfang, Song, Lian, Xu, Xuewen, You, Tao, Fan, Xin, Wang, Dongqing, Cheng, Fang, Zhu, Haitao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763460/ https://www.ncbi.nlm.nih.gov/pubmed/31558702 http://dx.doi.org/10.1038/s41419-019-1956-8

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