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NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis
Cancer-Associated Fibroblasts (CAFs) were shown to orchestrate tumour-promoting inflammation in multiple malignancies, including breast cancer. However, the molecular pathways that govern the inflammatory role of CAFs are poorly characterised. In this study we found that fibroblasts sense damage-ass...
Autores principales: | Ershaid, Nour, Sharon, Yoray, Doron, Hila, Raz, Yael, Shani, Ophir, Cohen, Noam, Monteran, Lea, Leider-Trejo, Leonor, Ben-Shmuel, Amir, Yassin, Muhammad, Gerlic, Motti, Ben-Baruch, Adit, Pasmanik-Chor, Metsada, Apte, Roni, Erez, Neta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763472/ https://www.ncbi.nlm.nih.gov/pubmed/31558756 http://dx.doi.org/10.1038/s41467-019-12370-8 |
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