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NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis

Cancer-Associated Fibroblasts (CAFs) were shown to orchestrate tumour-promoting inflammation in multiple malignancies, including breast cancer. However, the molecular pathways that govern the inflammatory role of CAFs are poorly characterised. In this study we found that fibroblasts sense damage-ass...

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Detalles Bibliográficos
Autores principales: Ershaid, Nour, Sharon, Yoray, Doron, Hila, Raz, Yael, Shani, Ophir, Cohen, Noam, Monteran, Lea, Leider-Trejo, Leonor, Ben-Shmuel, Amir, Yassin, Muhammad, Gerlic, Motti, Ben-Baruch, Adit, Pasmanik-Chor, Metsada, Apte, Roni, Erez, Neta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763472/
https://www.ncbi.nlm.nih.gov/pubmed/31558756
http://dx.doi.org/10.1038/s41467-019-12370-8

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