Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae

Herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent and relatively neuroinvasive in animal models compared with other wild-type HSV-1 strains. To identify the genetic determinants that lead to the unique phenotypes of the McKrae strain, we sequenced its genome with PacBio single-molecule...

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Autores principales: Jiao, Xiaoli, Sui, Hongyan, Lyons, Christopher, Tran, Bao, Sherman, Brad T., Imamichi, Tomozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763650/
https://www.ncbi.nlm.nih.gov/pubmed/31558635
http://dx.doi.org/10.1128/MRA.00993-19
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author Jiao, Xiaoli
Sui, Hongyan
Lyons, Christopher
Tran, Bao
Sherman, Brad T.
Imamichi, Tomozumi
author_facet Jiao, Xiaoli
Sui, Hongyan
Lyons, Christopher
Tran, Bao
Sherman, Brad T.
Imamichi, Tomozumi
author_sort Jiao, Xiaoli
collection PubMed
description Herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent and relatively neuroinvasive in animal models compared with other wild-type HSV-1 strains. To identify the genetic determinants that lead to the unique phenotypes of the McKrae strain, we sequenced its genome with PacBio single-molecule real-time (SMRT) technology and resolved the complete sequence.
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spelling pubmed-67636502019-10-15 Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae Jiao, Xiaoli Sui, Hongyan Lyons, Christopher Tran, Bao Sherman, Brad T. Imamichi, Tomozumi Microbiol Resour Announc Genome Sequences Herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent and relatively neuroinvasive in animal models compared with other wild-type HSV-1 strains. To identify the genetic determinants that lead to the unique phenotypes of the McKrae strain, we sequenced its genome with PacBio single-molecule real-time (SMRT) technology and resolved the complete sequence. American Society for Microbiology 2019-09-26 /pmc/articles/PMC6763650/ /pubmed/31558635 http://dx.doi.org/10.1128/MRA.00993-19 Text en Copyright © 2019 Jiao et al. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Genome Sequences
Jiao, Xiaoli
Sui, Hongyan
Lyons, Christopher
Tran, Bao
Sherman, Brad T.
Imamichi, Tomozumi
Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
title Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
title_full Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
title_fullStr Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
title_full_unstemmed Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
title_short Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae
title_sort complete genome sequence of herpes simplex virus 1 strain mckrae
topic Genome Sequences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763650/
https://www.ncbi.nlm.nih.gov/pubmed/31558635
http://dx.doi.org/10.1128/MRA.00993-19
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