Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal

Occupational exposure to respirable crystalline silica (cSiO(2)) has been etiologically linked to human autoimmunity. Intranasal instillation with cSiO(2) triggers profuse inflammation in the lung and onset of autoimmunity in lupus-prone mice; however, dietary supplementation with the omega-3 polyun...

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Detalles Bibliográficos
Autores principales: Wierenga, Kathryn A., Wee, Josephine, Gilley, Kristen N., Rajasinghe, Lichchavi D., Bates, Melissa A., Gavrilin, Mikhail A., Holian, Andrij, Pestka, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763728/
https://www.ncbi.nlm.nih.gov/pubmed/31616405
http://dx.doi.org/10.3389/fimmu.2019.02130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763728/
https://www.ncbi.nlm.nih.gov/pubmed/31616405
http://dx.doi.org/10.3389/fimmu.2019.02130

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