Alternating flexed-extended posturing in progressive supranuclear palsy

A 69-year-old man who had been bedridden in nursing home because of a 5- year history of progressive supranuclear palsy (PSP) was admitted due to aspiration pneumonia. Besides neck dystonia in extension, he showed “alternating flexed–extended posturing”, in which the arm was flexed on one side and e...

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Detalles Bibliográficos
Autores principales: Ishii, Nobuyuki, Mochizuki, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763747/
https://www.ncbi.nlm.nih.gov/pubmed/31579148
http://dx.doi.org/10.4081/ni.2019.8257
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author Ishii, Nobuyuki
Mochizuki, Hitoshi
author_facet Ishii, Nobuyuki
Mochizuki, Hitoshi
author_sort Ishii, Nobuyuki
collection PubMed
description A 69-year-old man who had been bedridden in nursing home because of a 5- year history of progressive supranuclear palsy (PSP) was admitted due to aspiration pneumonia. Besides neck dystonia in extension, he showed “alternating flexed–extended posturing”, in which the arm was flexed on one side and extended on the other. Magnetic resonance imaging of the brain revealed global cerebral atrophy that predominantly affected the cortex and midbrain. The mechanisms of complex posturing in late-stage PSP may sometimes be related to decortication and decerebration as well as dystonia, and “alternating flexed– extended posturing” might be one of the phenotypes of pathological progression in PSP.
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spelling pubmed-67637472019-10-02 Alternating flexed-extended posturing in progressive supranuclear palsy Ishii, Nobuyuki Mochizuki, Hitoshi Neurol Int Case Report A 69-year-old man who had been bedridden in nursing home because of a 5- year history of progressive supranuclear palsy (PSP) was admitted due to aspiration pneumonia. Besides neck dystonia in extension, he showed “alternating flexed–extended posturing”, in which the arm was flexed on one side and extended on the other. Magnetic resonance imaging of the brain revealed global cerebral atrophy that predominantly affected the cortex and midbrain. The mechanisms of complex posturing in late-stage PSP may sometimes be related to decortication and decerebration as well as dystonia, and “alternating flexed– extended posturing” might be one of the phenotypes of pathological progression in PSP. PAGEPress Publications, Pavia, Italy 2019-09-18 /pmc/articles/PMC6763747/ /pubmed/31579148 http://dx.doi.org/10.4081/ni.2019.8257 Text en ©Copyright: the Author(s), 2019 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ishii, Nobuyuki
Mochizuki, Hitoshi
Alternating flexed-extended posturing in progressive supranuclear palsy
title Alternating flexed-extended posturing in progressive supranuclear palsy
title_full Alternating flexed-extended posturing in progressive supranuclear palsy
title_fullStr Alternating flexed-extended posturing in progressive supranuclear palsy
title_full_unstemmed Alternating flexed-extended posturing in progressive supranuclear palsy
title_short Alternating flexed-extended posturing in progressive supranuclear palsy
title_sort alternating flexed-extended posturing in progressive supranuclear palsy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763747/
https://www.ncbi.nlm.nih.gov/pubmed/31579148
http://dx.doi.org/10.4081/ni.2019.8257
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