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Characterization of the Self-Resistance Mechanism to Dityromycin in the Streptomyces Producer Strain

Dityromycin is a peptide antibiotic isolated from the culture broth of the soil microorganism Streptomyces sp. strain AM-2504. Recent structural studies have shown that dityromycin targets the ribosomal protein S12 in the 30S ribosomal subunit, inhibiting translocation. Herein, by using in vitro pro...

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Detalles Bibliográficos
Autores principales: Fabbretti, Attilio, Çapuni, Retina, Giuliodori, Anna Maria, Cimarelli, Lucia, Miano, Antonino, Napolioni, Valerio, La Teana, Anna, Spurio, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763770/
https://www.ncbi.nlm.nih.gov/pubmed/31554724
http://dx.doi.org/10.1128/mSphere.00554-19