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Characterization of the Self-Resistance Mechanism to Dityromycin in the Streptomyces Producer Strain
Dityromycin is a peptide antibiotic isolated from the culture broth of the soil microorganism Streptomyces sp. strain AM-2504. Recent structural studies have shown that dityromycin targets the ribosomal protein S12 in the 30S ribosomal subunit, inhibiting translocation. Herein, by using in vitro pro...
Autores principales: | Fabbretti, Attilio, Çapuni, Retina, Giuliodori, Anna Maria, Cimarelli, Lucia, Miano, Antonino, Napolioni, Valerio, La Teana, Anna, Spurio, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763770/ https://www.ncbi.nlm.nih.gov/pubmed/31554724 http://dx.doi.org/10.1128/mSphere.00554-19 |
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