Cargando…

Clustering of Activated CD8 T Cells Around Malaria-Infected Hepatocytes Is Rapid and Is Driven by Antigen-Specific Cells

Malaria, a disease caused by parasites of the Plasmodium genus, begins when Plasmodium-infected mosquitoes inject malaria sporozoites while searching for blood. Sporozoites migrate from the skin via blood to the liver, infect hepatocytes, and form liver stages which in mice 48 h later escape into bl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kelemen, Reka K., Rajakaruna, Harshana, Cockburn, Ian A., Ganusov, Vitaly V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764016/ https://www.ncbi.nlm.nih.gov/pubmed/31616407 http://dx.doi.org/10.3389/fimmu.2019.02153

Ejemplares similares

A New Method Based on the von Mises-Fisher Distribution Shows that a Minority of Liver-Localized CD8 T Cells Display Hard-To-Detect Attraction to Plasmodium-Infected Hepatocytes
por: Zenkov, Viktor S., et al.
Publicado: (2022)

Dynamical regulations on mobility and vaccinations for controlling COVID-19 spread
por: Rajakaruna, Mevan, et al.
Publicado: (2022)

PASCAR: a multiscale framework to explore the design space of constitutive and inducible CAR T cells
por: Rajakaruna, Harshana, et al.
Publicado: (2023)

Defining Kinetic Properties of HIV-Specific CD8(+) T-Cell Responses in Acute Infection
por: Yang, Yiding, et al.
Publicado: (2019)

Brain-localized CD4 and CD8 T cells perform correlated random walks and not Levy walks
por: Patel, Dhruv, et al.
Publicado: (2023)

Optimizing methods to estimate zooplankton concentration based on generalized patterns of patchiness inside ballast tanks and ballast water discharges
por: Bailey, Sarah A., et al.
Publicado: (2017)

Cellular and population plasticity of helper CD4(+) T cell responses
por: Magombedze, Gesham, et al.
Publicado: (2013)

How Does Cross-Reactive Stimulation Affect the Longevity of CD8+ T Cell Memory?
por: Ganusov, Vitaly V, et al.
Publicado: (2006)

Correction: How Does Cross-Reactive Stimulation Affect the Longevity of CD8+ T Cell Memory?
por: Ganusov, Vitaly V, et al.
Publicado: (2006)

Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites
por: Cockburn, Ian A., et al.
Publicado: (2010)

Killing of Targets by CD8(+) T Cells in the Mouse Spleen Follows the Law of Mass Action
por: Ganusov, Vitaly V., et al.
Publicado: (2011)

Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo
por: Cockburn, Ian A., et al.
Publicado: (2011)

Lymph-Node Resident CD8α(+) Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8(+) T Cell Responses
por: Radtke, Andrea J., et al.
Publicado: (2015)

Rapid clearance of malaria circumsporozoite protein (CS) by hepatocytes
Publicado: (1994)

Linear scaling between microbial predator and prey densities in the global ocean
por: Rajakaruna, Harshana, et al.
Publicado: (2022)

CD4(+) T Cells Modulate Expansion and Survival but Not Functional Properties of Effector and Memory CD8(+) T Cells Induced by Malaria Sporozoites
por: Overstreet, Michael G., et al.
Publicado: (2011)

Competition for Antigen between Th1 and Th2 Responses Determines the Timing of the Immune Response Switch during Mycobaterium avium Subspecies paratuberulosis Infection in Ruminants
por: Magombedze, Gesham, et al.
Publicado: (2014)

CLUSTER OF DIFFERENTIATION (CD) ANTIGENS
Publicado: (2004)

Experimental determination of the force of malaria infection reveals a non-linear relationship to mosquito sporozoite loads
por: Aleshnick, Maya, et al.
Publicado: (2020)

Optimizing performance of nonparametric species richness estimators under constrained sampling
por: Rajakaruna, Harshana, et al.
Publicado: (2016)

Mtb-Specific CD27(low) CD4 T Cells as Markers of Lung Tissue Destruction during Pulmonary Tuberculosis in Humans
por: Nikitina, Irina Yu, et al.
Publicado: (2012)

Unique transcriptional profile of liver-resident memory CD8(+) T cells induced by immunization with malaria sporozoites
por: Tse, Sze-Wah, et al.
Publicado: (2013)

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8(+) T Cell Tolerance Development
por: Damo, Martina, et al.
Publicado: (2021)

Effective intrahepatic CD8+ T-cell immune responses are induced by low but not high numbers of antigen-expressing hepatocytes
por: Ochel, Aaron, et al.
Publicado: (2016)

Cytotoxic T Lymphocytes Control Growth of B16 Tumor Cells in Collagen–Fibrin Gels by Cytolytic and Non-Lytic Mechanisms
por: Majumder, Barun, et al.
Publicado: (2023)

Priming of CD8(+) T Cell Responses to Liver Stage Malaria Parasite Antigens
por: Corradin, Giampietro, et al.
Publicado: (2014)

Time Intervals in Sequence Sampling, Not Data Modifications, Have a Major Impact on Estimates of HIV Escape Rates
por: Ganusov, Vitaly V.
Publicado: (2018)

Strong Inference in Mathematical Modeling: A Method for Robust Science in the Twenty-First Century
por: Ganusov, Vitaly V.
Publicado: (2016)

Appropriate sampling and long follow-up are required to rigorously evaluate longevity of humoral memory after Vaccination
por: Ganusov, Vitaly V.
Publicado: (2023)

Multiplex Human Malaria Array: Quantifying Antigens for Malaria Rapid Diagnostics
por: Jang, Ihn Kyung, et al.
Publicado: (2020)

Memory Phenotype CD4 T Cells Undergoing Rapid, Nonburst-Like, Cytokine-Driven Proliferation Can Be Distinguished from Antigen-Experienced Memory Cells
por: Younes, Souheil-Antoine, et al.
Publicado: (2011)

Mathematical modeling suggests cytotoxic T lymphocytes control growth of B16 tumor cells in collagin-fibrin gels by cytolytic and non-lytic mechanisms
por: Majumder, Barun, et al.
Publicado: (2023)

Antigen-driven focal inflammatory death of malaria liver stages
por: Bayarsaikhan, Ganchimeg, et al.
Publicado: (2015)

Severe Tuberculosis in Humans Correlates Best with Neutrophil Abundance and Lymphocyte Deficiency and Does Not Correlate with Antigen-Specific CD4 T-Cell Response
por: Panteleev, Alexander V., et al.
Publicado: (2017)

An Inducible Transgenic Mouse Model for Immune Mediated Hepatitis Showing Clearance of Antigen Expressing Hepatocytes by CD8+ T Cells
por: Cebula, Marcin, et al.
Publicado: (2013)

Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells
por: Siller, Richard, et al.
Publicado: (2015)

Clonal Structure of Rapid-Onset MDV-Driven CD4+ Lymphomas and Responding CD8+ T Cells
por: Mwangi, William N., et al.
Publicado: (2011)

Cross-presentation of malaria antigen by brain microvessels: why CD8(+) T cells are critical for the pathogenesis of experimental cerebral malaria
por: Yui, Katsuyuki
Publicado: (2013)

IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites
por: Morrot, Alexandre, et al.
Publicado: (2005)

Antigen-driven EGR2 expression is required for exhausted CD8(+) T cell stability and maintenance
por: Wagle, Mayura V., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_10rgko1cud5h4oaiohb536lhij