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Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological features and management, a single-center experience
Solid pseudopapillary neoplasm of the pancreas is a rare tumor of low malignancy that occurs most often in females. The study describes the clinicopathologic characteristics of the tumor and common differential diagnoses. Data were collected from a prospectively maintained database. Of 1661 patients...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764028/ https://www.ncbi.nlm.nih.gov/pubmed/31598207 http://dx.doi.org/10.1177/2036361319878513 |
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author | Hansen, Carsten Palnaes Kristensen, Thomas Skaarup Storkholm, Jan Henrik Federspiel, Birgitte Hartnack |
author_facet | Hansen, Carsten Palnaes Kristensen, Thomas Skaarup Storkholm, Jan Henrik Federspiel, Birgitte Hartnack |
author_sort | Hansen, Carsten Palnaes |
collection | PubMed |
description | Solid pseudopapillary neoplasm of the pancreas is a rare tumor of low malignancy that occurs most often in females. The study describes the clinicopathologic characteristics of the tumor and common differential diagnoses. Data were collected from a prospectively maintained database. Of 1661 patients operated for pancreatic tumors between January 2001 and September 2018, 15 patients were recorded. Patients included 12 females and 3 males, median age 40 (range 10 -87) years. Computed tomography or magnetic resonance imaging was diagnostic in eight patients and a preoperative biopsy in eight out of 10 patients. Median tumor size was 5 cm (range 2 -16 cm), 12 tumors were in the head, six in the body, and three in the tail of the gland. All patients except one had radical resection including one with hepatic and lymph node metastases, no patient underwent oncologic treatment. All patients are alive from 17.5 to 209.4 months postoperatively and without recurrence. Radical operation is usually curative and should also be offered to patients with metastases or recurrence as oncologic treatment has limited effect. |
format | Online Article Text |
id | pubmed-6764028 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-67640282019-10-09 Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological features and management, a single-center experience Hansen, Carsten Palnaes Kristensen, Thomas Skaarup Storkholm, Jan Henrik Federspiel, Birgitte Hartnack Rare Tumors Original Article Solid pseudopapillary neoplasm of the pancreas is a rare tumor of low malignancy that occurs most often in females. The study describes the clinicopathologic characteristics of the tumor and common differential diagnoses. Data were collected from a prospectively maintained database. Of 1661 patients operated for pancreatic tumors between January 2001 and September 2018, 15 patients were recorded. Patients included 12 females and 3 males, median age 40 (range 10 -87) years. Computed tomography or magnetic resonance imaging was diagnostic in eight patients and a preoperative biopsy in eight out of 10 patients. Median tumor size was 5 cm (range 2 -16 cm), 12 tumors were in the head, six in the body, and three in the tail of the gland. All patients except one had radical resection including one with hepatic and lymph node metastases, no patient underwent oncologic treatment. All patients are alive from 17.5 to 209.4 months postoperatively and without recurrence. Radical operation is usually curative and should also be offered to patients with metastases or recurrence as oncologic treatment has limited effect. SAGE Publications 2019-09-26 /pmc/articles/PMC6764028/ /pubmed/31598207 http://dx.doi.org/10.1177/2036361319878513 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Hansen, Carsten Palnaes Kristensen, Thomas Skaarup Storkholm, Jan Henrik Federspiel, Birgitte Hartnack Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological features and management, a single-center experience |
title | Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological
features and management, a single-center experience |
title_full | Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological
features and management, a single-center experience |
title_fullStr | Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological
features and management, a single-center experience |
title_full_unstemmed | Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological
features and management, a single-center experience |
title_short | Solid pseudopapillary neoplasm of the pancreas: Clinical-pathological
features and management, a single-center experience |
title_sort | solid pseudopapillary neoplasm of the pancreas: clinical-pathological
features and management, a single-center experience |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764028/ https://www.ncbi.nlm.nih.gov/pubmed/31598207 http://dx.doi.org/10.1177/2036361319878513 |
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