Functional rare variants influence the clinical response to anti-TNF therapy in Crohn’s disease

BACKGROUND: The effect of low-frequency functional variation on anti-tumor necrosis factor alpha (TNF) response in Crohn’s disease (CD) patients remains unexplored. The objective of this study was to investigate the impact of functional rare variants in clinical response to anti-TNF therapy in CD. M...

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Detalles Bibliográficos
Autores principales: Chaparro, María, Aterido, Adrià, Guerra, Iván, Iborra, Marisa, Cabriada, Jose Luis, Bujanda, Luis, Taxonera, Carlos, García-Sánchez, Valle, Marín-Jiménez, Ignacio, Barreiro-de Acosta, Manuel, Vera, Isabel, Martín-Arranz, Maria Dolores, Hernández-Breijo, Borja, Mesonero, Francisco, Sempere, Laura, Gomollón, Fernando, Hinojosa, Joaquín, Bermejo, Fernando, Beltrán, Belén, Rodríguez-Pescador, Ainhoa, Banales, Jesús María, Olivares, David, Aguilar-Melero, Patricia, Menchén, Luis, Ferreiro-Iglesias, Rocío, Blazquez Gómez, Isabel, Benitez García, Beatriz, Guijarro, Luis G, Marin, Alicia C, Bernardo, David, Marsal, Sara, Julia, Antonio, Gisbert, Javier P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764039/
https://www.ncbi.nlm.nih.gov/pubmed/31598133
http://dx.doi.org/10.1177/1756284819867848

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