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Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its active metabolite, the 2-hydroxy-4-trifluoromethylbenzoic acid (HTB). We present here an investigation on HTB photobinding to human serum al...

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Detalles Bibliográficos
Autores principales: Molins-Molina, Oscar, Pérez-Ruiz, Raúl, Lence, Emilio, González-Bello, Concepción, Miranda, Miguel A., Jiménez, M. Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764118/
https://www.ncbi.nlm.nih.gov/pubmed/31616294
http://dx.doi.org/10.3389/fphar.2019.01028