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An Experimental Slope Method for a More Accurate Measurement of Relative Radiation Doses using Radiographic and Radiochromic Films and Its Application to Megavoltage Small-Field Dosimetry

PURPOSE: An experimental method using the linear portion of the relative film dose–response curve for radiographic and radiochromic films is presented, which can be used to determine the relative depth doses in a variety of very small, medium, and large radiation fields and relative output factors (...

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Detalles Bibliográficos
Autores principales: Holla, Raghavendra, Khanna, D., Pillai, Bhaskaran K., Jafar Ali, K. V., Renil Mon, P. S., Clinto, C. O., Ganesh, Tharmarnadar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764177/
https://www.ncbi.nlm.nih.gov/pubmed/31576063
http://dx.doi.org/10.4103/jmp.JMP_17_19
Descripción
Sumario:PURPOSE: An experimental method using the linear portion of the relative film dose–response curve for radiographic and radiochromic films is presented, which can be used to determine the relative depth doses in a variety of very small, medium, and large radiation fields and relative output factors (ROFs) for small fields. MATERIALS AND METHODS: The film slope (FS) method was successfully applied to obtain the percentage depth doses (PDDs) for external beams of photon and electrons from a Synergy linear accelerator (Elekta AB, Stockholm, Sweden) under reference conditions of 10 cm × 10 cm for photon beam and nominal 10 cm × 10 cm size applicator for electron beam. For small-field dosimetry, the FS method was applied to EDR2 films (Carestream Health, Rochester, NY) for 6 MV photon beam from a linac (Elekta AB, Stockholm, Sweden) and small, circular radiosurgery cones (Elekta AB, Stockholm, Sweden) with diameters of 5, 7.5, 10, 12.5, and 15 mm. The ROFs for all these cones and central axis PDDs for 5, 10, and 15 mm diameter cones were determined at source-to-surface distance of 100 cm. The ROFs for small fields of CyberKnife system were determined using this technique with Gafchromic EBT3 film (Ashland, NJ, USA). The PDDs and ROFs were compared with ion chamber (IC) and Monte Carlo (MC) simulated values. RESULTS: The maximum percentage deviation of PDD(FS) with PDD(IC) for 4, 6, and 15 MV photon beams was within 1.9%, 2.5%, and 1.4%, respectively, up to 20-cm depth. The maximum percentage deviation of PDD(FS) with PDD(IC) for electron beams was within 3% for energy range studied of 8–15 MeV. The gamma passing rates of PDD(FS) with PDD(IC) were above 96.5% with maximum gamma value of >2, occurring at the zero depths for 4, 6, and 15 MV photons. For electron beams, the gamma passing rates between PDD(FS) with PDD(IC) were above 97.7% with a maximum gamma value of 0.9, 1.3, and 0.7 occurring at the zero depth for 8, 12, and 15 MeV. For small field of 5-mm cone, the ROF(FS) was 0.665 ± 0.021 as compared to 0.674 by MC method. The maximum percentage deviation between PDD(FS) and PDD(MC) was 3% for 5 mm and 10 mm and 2% for 15 mm cones with 1D gamma passing rates, respectively, of 95.5%, 96%, and 98%. For CyberKnife system, the ROF(FS) using EBT3 film and MC published values agrees within 0.2% for for 5 mm cone. CONCLUSIONS: The authors have developed a novel and more accurate method for the relative dosimetry of photon and electron beams. This offers a unique method to determine PDD and ROF with a high spatial resolution in fields of steep dose gradient, especially in small fields.