The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India

Robertsonian translocation is a subtype of balanced translocation involving two acrocentric chromosomes. Individuals who are carrier of this abnormality are at increased risk of infertility or bad obstetric history. This case is reported with the aim to describe a male who presented with nonobstruct...

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Detalles Bibliográficos
Autores principales: Singhal, Paresh, Malik, Ajay, Naredi, Nikita, Pranaya, Gurmeet, Agrawal, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764225/
https://www.ncbi.nlm.nih.gov/pubmed/31576085
http://dx.doi.org/10.4103/jhrs.JHRS_13_19
Descripción
Sumario:Robertsonian translocation is a subtype of balanced translocation involving two acrocentric chromosomes. Individuals who are carrier of this abnormality are at increased risk of infertility or bad obstetric history. This case is reported with the aim to describe a male who presented with nonobstructive azoospermia at a tertiary care center. The individual was phenotypically normal but carrier of a Robertsonian translocation of two acrocentric chromosomes. With this literature, we emphasize that conventional cytogenetic is an essential diagnostic tool for screening genetic factors in infertility.

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