The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India

Robertsonian translocation is a subtype of balanced translocation involving two acrocentric chromosomes. Individuals who are carrier of this abnormality are at increased risk of infertility or bad obstetric history. This case is reported with the aim to describe a male who presented with nonobstruct...

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Autores principales: Singhal, Paresh, Malik, Ajay, Naredi, Nikita, Pranaya, Gurmeet, Agrawal, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764225/
https://www.ncbi.nlm.nih.gov/pubmed/31576085
http://dx.doi.org/10.4103/jhrs.JHRS_13_19
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author Singhal, Paresh
Malik, Ajay
Naredi, Nikita
Pranaya, Gurmeet
Agrawal, Amit
author_facet Singhal, Paresh
Malik, Ajay
Naredi, Nikita
Pranaya, Gurmeet
Agrawal, Amit
author_sort Singhal, Paresh
collection PubMed
description Robertsonian translocation is a subtype of balanced translocation involving two acrocentric chromosomes. Individuals who are carrier of this abnormality are at increased risk of infertility or bad obstetric history. This case is reported with the aim to describe a male who presented with nonobstructive azoospermia at a tertiary care center. The individual was phenotypically normal but carrier of a Robertsonian translocation of two acrocentric chromosomes. With this literature, we emphasize that conventional cytogenetic is an essential diagnostic tool for screening genetic factors in infertility.
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spelling pubmed-67642252019-10-01 The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India Singhal, Paresh Malik, Ajay Naredi, Nikita Pranaya, Gurmeet Agrawal, Amit J Hum Reprod Sci Case Report Robertsonian translocation is a subtype of balanced translocation involving two acrocentric chromosomes. Individuals who are carrier of this abnormality are at increased risk of infertility or bad obstetric history. This case is reported with the aim to describe a male who presented with nonobstructive azoospermia at a tertiary care center. The individual was phenotypically normal but carrier of a Robertsonian translocation of two acrocentric chromosomes. With this literature, we emphasize that conventional cytogenetic is an essential diagnostic tool for screening genetic factors in infertility. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6764225/ /pubmed/31576085 http://dx.doi.org/10.4103/jhrs.JHRS_13_19 Text en Copyright: © 2019 Journal of Human Reproductive Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Singhal, Paresh
Malik, Ajay
Naredi, Nikita
Pranaya, Gurmeet
Agrawal, Amit
The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India
title The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India
title_full The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India
title_fullStr The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India
title_full_unstemmed The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India
title_short The Robertsonian translocation of ‘21/22’ in Nonobstructive Azoospermia: A Rare Case Report from India
title_sort robertsonian translocation of ‘21/22’ in nonobstructive azoospermia: a rare case report from india
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764225/
https://www.ncbi.nlm.nih.gov/pubmed/31576085
http://dx.doi.org/10.4103/jhrs.JHRS_13_19
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