Pyridoxamine Supplementation Effectively Reverses the Abnormal Phenotypes of Zebrafish Larvae With PNPO Deficiency

Neonatal epileptic encephalopathy (NEE), as a result of pyridoxine 5′-phosphate oxidase (PNPO) deficiency, is a rare neural disorder characterized by intractable seizures and usually leads to early infant death. The clinical phenotypes do not respond to antiepileptic drugs but are alleviated in most...

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Detalles Bibliográficos
Autores principales: Chen, Po-Yuan, Tu, Hung-Chi, Schirch, Verne, Safo, Martin K., Fu, Tzu-Fun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764245/
https://www.ncbi.nlm.nih.gov/pubmed/31616300
http://dx.doi.org/10.3389/fphar.2019.01086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764245/
https://www.ncbi.nlm.nih.gov/pubmed/31616300
http://dx.doi.org/10.3389/fphar.2019.01086

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