Dexmedetomidine inhibits the NF-κB pathway and NLRP3 inflammasome to attenuate papain-induced osteoarthritis in rats

Context: Dexmedetomidine (Dex) has been reported to have an anti-inflammatory effect. However, its role on osteoarthritis (OA) has not been explored. Objective: This study investigates the effect of Dex on OA rat model induced by papain. Materials and methods: The OA Wistar rat model was induced by...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Fang, Yan, Feng-Feng, Liu, Yue-Peng, Cong, Yan, Sun, Ke-Fu, He, Xue-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764405/
https://www.ncbi.nlm.nih.gov/pubmed/31545916
http://dx.doi.org/10.1080/13880209.2019.1651874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764405/
https://www.ncbi.nlm.nih.gov/pubmed/31545916
http://dx.doi.org/10.1080/13880209.2019.1651874

Ejemplares similares