Cargando…

Balancing Selection Drives the Maintenance of Genetic Variation in Drosophila Antimicrobial Peptides

Genes involved in immune defense against pathogens provide some of the most well-known examples of both directional and balancing selection. Antimicrobial peptides (AMPs) are innate immune effector genes, playing a key role in pathogen clearance in many species, including Drosophila. Conflicting lin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chapman, Joanne R, Hill, Tom, Unckless, Robert L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764478/ https://www.ncbi.nlm.nih.gov/pubmed/31504505 http://dx.doi.org/10.1093/gbe/evz191

Ejemplares similares

The potential for adaptive maintenance of diversity in insect antimicrobial peptides
por: Unckless, Robert L., et al.
Publicado: (2016)

The Genetic Basis of Natural Variation in Drosophila melanogaster Immune Defense against Enterococcus faecalis
por: Chapman, Joanne R, et al.
Publicado: (2020)

A suite of selective pressures supports the maintenance of alleles of a Drosophila immune peptide
por: Mullinax, Sarah R., et al.
Publicado: (2023)

The Genome of Drosophila innubila Reveals Lineage-Specific Patterns of Selection in Immune Genes
por: Hill, Tom, et al.
Publicado: (2019)

An assessment of the immune costs associated with meiotic drive elements in Drosophila
por: Lea, Jenna Kay, et al.
Publicado: (2019)

The Genetic Basis of Natural Variation in Drosophila (Diptera: Drosophilidae) Virgin Egg Retention
por: Akhund-Zade, Jamilla, et al.
Publicado: (2017)

A Deep Learning Approach for Detecting Copy Number Variation in Next-Generation Sequencing Data
por: Hill, Tom, et al.
Publicado: (2019)

The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster
por: Smith, Brittny R., et al.
Publicado: (2023)

Baculovirus Molecular Evolution via Gene Turnover and Recurrent Positive Selection of Key Genes
por: Hill, Tom, et al.
Publicado: (2017)

Rapid divergence of the male reproductive proteins in the Drosophila dunni group and implications for postmating incompatibilities between species
por: Hill, Tom, et al.
Publicado: (2021)

The Complex Contributions of Genetics and Nutrition to Immunity in Drosophila melanogaster
por: Unckless, Robert L., et al.
Publicado: (2015)

A DNA Virus of Drosophila
por: Unckless, Robert L.
Publicado: (2011)

Dynamic Evolution of Antimicrobial Peptides Underscores Trade-Offs Between Immunity and Ecological Fitness
por: Hanson, Mark A., et al.
Publicado: (2019)

Positive Selection and Horizontal Gene Transfer in the Genome of a Male-Killing Wolbachia
por: Hill, Tom, et al.
Publicado: (2021)

Hidden genetic variation shapes the structure of functional elements in Drosophila
por: Chakraborty, Mahul, et al.
Publicado: (2017)

Artificial selection reveals the role of transcriptional constraints in the maintenance of life history variation
por: Pick, Joel L., et al.
Publicado: (2020)

Sex peptide receptor-regulated polyandry modulates the balance of pre- and post-copulatory sexual selection in Drosophila
por: Morimoto, Juliano, et al.
Publicado: (2019)

A single amino acid polymorphism in natural Metchnikowin alleles of Drosophila results in systemic immunity and life history tradeoffs
por: Perlmutter, Jessamyn I., et al.
Publicado: (2023)

The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila
por: Parvy, Jean-Philippe, et al.
Publicado: (2019)

Recurrent evolution of high virulence in isolated populations of a DNA virus
por: Hill, Tom, et al.
Publicado: (2020)

Antimicrobial peptides extend lifespan in Drosophila
por: Loch, Gerrit, et al.
Publicado: (2017)

Balancing Selection at a Frog Antimicrobial Peptide Locus: Fluctuating Immune Effector Alleles?
por: Tennessen, Jacob A., et al.
Publicado: (2008)

Draft Genome Sequence of Lysinibacillus fusiformis Strain Juneja, a Laboratory-Derived Pathogen of Drosophila melanogaster
por: Smith, Brittny R., et al.
Publicado: (2018)

A Genome-Wide Association Study for Nutritional Indices in Drosophila
por: Unckless, Robert L., et al.
Publicado: (2015)

Evidence that natural selection maintains genetic variation for sleep in Drosophila melanogaster
por: Svetec, Nicolas, et al.
Publicado: (2015)

Genotype‐by‐environment interactions drive the maintenance of genetic variation in a Salmo trutta L. hybrid zone
por: Folio, Dorinda Marie, et al.
Publicado: (2021)

Evolutionary Dynamics of Male Reproductive Genes in the Drosophila virilis Subgroup
por: Ahmed-Braimah, Yasir H., et al.
Publicado: (2017)

Wolbachia enhances the survival of Drosophila infected with fungal pathogens
por: Perlmutter, Jessamyn I., et al.
Publicado: (2023)

Correction for Smith and Unckless, “Draft Genome Sequence of Lysinibacillus fusiformis Strain Juneja, a Laboratory-Derived Pathogen of Drosophila melanogaster”
por: Smith, Brittny R., et al.
Publicado: (2018)

Characterizing Recurrent Positive Selection at Fast-Evolving Genes in Drosophila miranda and Drosophila pseudoobscura
por: Jensen, Jeffrey D., et al.
Publicado: (2010)

Deep mutational scanning and machine learning uncover antimicrobial peptide features driving membrane selectivity
por: Randall, Justin R., et al.
Publicado: (2023)

Deep mutational scanning and machine learning uncover antimicrobial peptide features driving membrane selectivity
por: Randall, Justin R., et al.
Publicado: (2023)

The Population Genetics of Evolutionary Rescue
por: Orr, H. Allen, et al.
Publicado: (2014)

Variational Autoencoder for Generation of Antimicrobial Peptides
por: Dean, Scott N., et al.
Publicado: (2020)

Comparing Selection on S. aureus between Antimicrobial Peptides and Common Antibiotics
por: Dobson, Adam J., et al.
Publicado: (2013)

Structure–activity relationship of an antimicrobial peptide, Phylloseptin-PHa: balance of hydrophobicity and charge determines the selectivity of bioactivities
por: Liu, Yuzhang, et al.
Publicado: (2019)

Genetic Variation for Cardiac Dysfunction in Drosophila
por: Ocorr, Karen A., et al.
Publicado: (2007)

Induction and inhibition of Drosophila X chromosome gene expression are both impeded by the dosage compensation complex
por: Meisel, Richard P, et al.
Publicado: (2022)

Dominance reversals and the maintenance of genetic variation for fitness
por: Connallon, Tim, et al.
Publicado: (2019)

The maintenance of standing genetic variation: Gene flow vs. selective neutrality in Atlantic stickleback fish
por: Haenel, Quiterie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jo0nbi63q2unm4tmr5gdib5ohs