Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report

BACKGROUND: Although aspirin and adrenaline are the guideline-recommended treatments for acute coronary syndrome (ACS) and anaphylaxis, both regimens can contribute to clinical worsening in the setting of concurrent ACS and anaphylaxis which is called allergic angina or Kounis syndrome. CASE SUMMARY...

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Detalles Bibliográficos
Autores principales: Toya, Takumi, Kagami, Kazuki, Adachi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764556/
https://www.ncbi.nlm.nih.gov/pubmed/31660504
http://dx.doi.org/10.1093/ehjcr/ytz143
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author Toya, Takumi
Kagami, Kazuki
Adachi, Takeshi
author_facet Toya, Takumi
Kagami, Kazuki
Adachi, Takeshi
author_sort Toya, Takumi
collection PubMed
description BACKGROUND: Although aspirin and adrenaline are the guideline-recommended treatments for acute coronary syndrome (ACS) and anaphylaxis, both regimens can contribute to clinical worsening in the setting of concurrent ACS and anaphylaxis which is called allergic angina or Kounis syndrome. CASE SUMMARY: A 62-year-old woman with food-dependent exercise-induced anaphylaxis developed ACS after intramuscular injection of adrenaline for the treatment of anaphylaxis, whereas administered aspirin for the treatment of ACS exacerbated anaphylaxis. DISCUSSION: Our case underlines the importance of tailored treatment based on the underlying pathophysiology of individual patients. Clopidogrel and glucagon might be a better alternative for the treatment of Kounis syndrome.
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spelling pubmed-67645562019-10-02 Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report Toya, Takumi Kagami, Kazuki Adachi, Takeshi Eur Heart J Case Rep Case Reports BACKGROUND: Although aspirin and adrenaline are the guideline-recommended treatments for acute coronary syndrome (ACS) and anaphylaxis, both regimens can contribute to clinical worsening in the setting of concurrent ACS and anaphylaxis which is called allergic angina or Kounis syndrome. CASE SUMMARY: A 62-year-old woman with food-dependent exercise-induced anaphylaxis developed ACS after intramuscular injection of adrenaline for the treatment of anaphylaxis, whereas administered aspirin for the treatment of ACS exacerbated anaphylaxis. DISCUSSION: Our case underlines the importance of tailored treatment based on the underlying pathophysiology of individual patients. Clopidogrel and glucagon might be a better alternative for the treatment of Kounis syndrome. Oxford University Press 2019-08-28 /pmc/articles/PMC6764556/ /pubmed/31660504 http://dx.doi.org/10.1093/ehjcr/ytz143 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Reports
Toya, Takumi
Kagami, Kazuki
Adachi, Takeshi
Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
title Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
title_full Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
title_fullStr Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
title_full_unstemmed Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
title_short Friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
title_sort friend or foe: food-dependent exercise-induced anaphylaxis associated with acute coronary syndrome aggravated by adrenaline and aspirin: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764556/
https://www.ncbi.nlm.nih.gov/pubmed/31660504
http://dx.doi.org/10.1093/ehjcr/ytz143
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AT adachitakeshi friendorfoefooddependentexerciseinducedanaphylaxisassociatedwithacutecoronarysyndromeaggravatedbyadrenalineandaspirinacasereport

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