Multiple Intracranial Rosai-Dorfman Disease: A Case Report

Rosai-Dorfman disease is an uncommon lymphoproliferative disorder, and multiple intracranial involvement in disseminated disease is exceedingly rare. We present a case of a 52 year-old female who presented with intractable headaches and a history of Rosai-Dorfman disease unresponsive to chemo- and r...

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Detalles Bibliográficos
Autores principales: Krueger, Evan M, Brown, Henry G, Schaible, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764651/
https://www.ncbi.nlm.nih.gov/pubmed/31576281
http://dx.doi.org/10.7759/cureus.5292
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author Krueger, Evan M
Brown, Henry G
Schaible, Keith
author_facet Krueger, Evan M
Brown, Henry G
Schaible, Keith
author_sort Krueger, Evan M
collection PubMed
description Rosai-Dorfman disease is an uncommon lymphoproliferative disorder, and multiple intracranial involvement in disseminated disease is exceedingly rare. We present a case of a 52 year-old female who presented with intractable headaches and a history of Rosai-Dorfman disease unresponsive to chemo- and radiation therapies. She was found to have new multiple intracranial masses that were treated with surgical excision. Pathology confirmed a diagnosis of intracranial Rosai-Dorfman. The disease presentation, radiographic appearance, histology, treatment, and prognosis are briefly reviewed.
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spelling pubmed-67646512019-10-01 Multiple Intracranial Rosai-Dorfman Disease: A Case Report Krueger, Evan M Brown, Henry G Schaible, Keith Cureus Pathology Rosai-Dorfman disease is an uncommon lymphoproliferative disorder, and multiple intracranial involvement in disseminated disease is exceedingly rare. We present a case of a 52 year-old female who presented with intractable headaches and a history of Rosai-Dorfman disease unresponsive to chemo- and radiation therapies. She was found to have new multiple intracranial masses that were treated with surgical excision. Pathology confirmed a diagnosis of intracranial Rosai-Dorfman. The disease presentation, radiographic appearance, histology, treatment, and prognosis are briefly reviewed. Cureus 2019-07-31 /pmc/articles/PMC6764651/ /pubmed/31576281 http://dx.doi.org/10.7759/cureus.5292 Text en Copyright © 2019, Krueger et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Krueger, Evan M
Brown, Henry G
Schaible, Keith
Multiple Intracranial Rosai-Dorfman Disease: A Case Report
title Multiple Intracranial Rosai-Dorfman Disease: A Case Report
title_full Multiple Intracranial Rosai-Dorfman Disease: A Case Report
title_fullStr Multiple Intracranial Rosai-Dorfman Disease: A Case Report
title_full_unstemmed Multiple Intracranial Rosai-Dorfman Disease: A Case Report
title_short Multiple Intracranial Rosai-Dorfman Disease: A Case Report
title_sort multiple intracranial rosai-dorfman disease: a case report
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764651/
https://www.ncbi.nlm.nih.gov/pubmed/31576281
http://dx.doi.org/10.7759/cureus.5292
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