Gene expression profiling of skeletal myogenesis in human embryonic stem cells reveals a potential cascade of transcription factors regulating stages of myogenesis, including quiescent/activated satellite cell-like gene expression

Human embryonic stem cell (hESC)-derived skeletal muscle progenitors (SMP)—defined as PAX7-expressing cells with myogenic potential—can provide an abundant source of donor material for muscle stem cell therapy. As in vitro myogenesis is decoupled from in vivo timing and 3D-embryo structure, it is im...

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Detalles Bibliográficos
Autores principales: Shelton, Michael, Ritso, Morten, Liu, Jun, O’Neil, Daniel, Kocharyan, Avetik, Rudnicki, Michael A., Stanford, William L., Skerjanc, Ilona S., Blais, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764674/
https://www.ncbi.nlm.nih.gov/pubmed/31560727
http://dx.doi.org/10.1371/journal.pone.0222946

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