Cargando…

Circulating IGFBP‐2: a novel biomarker for incident dementia

OBJECTIVE: To determine the association between plasma insulin‐like growth factor binding protein 2 (IGFBP‐2) and cognitive outcomes. METHODS: We measured plasma IGFBP‐2 levels in 1596 (53% women, mean age 68.7 [SD 5.7] years) dementia‐free Framingham Offspring cohort participants between 1998 and 2...

Descripción completa

Detalles Bibliográficos
Autores principales:	McGrath, Emer R., Himali, Jayandra J., Levy, Daniel, Conner, Sarah C., DeCarli, Charles S., Pase, Matthew P., Courchesne, Paul, Satizabal, Claudia L., Vasan, Ramachandran S., Beiser, Alexa S., Seshadri, Sudha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764739/ https://www.ncbi.nlm.nih.gov/pubmed/31373442 http://dx.doi.org/10.1002/acn3.50854

Ejemplares similares

Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study
por: McGrath, Emer R., et al.
Publicado: (2019)

Growth Differentiation Factor 15 and NT‐proBNP as Blood‐Based Markers of Vascular Brain Injury and Dementia
por: McGrath, Emer R., et al.
Publicado: (2020)

Circulating ceramide ratios and risk of vascular brain aging and dementia
por: McGrath, Emer R., et al.
Publicado: (2020)

Identifying Blood Biomarkers for Dementia Using Machine Learning Methods in the Framingham Heart Study
por: Lin, Honghuang, et al.
Publicado: (2022)

Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902–1985
por: DeCarli, Charles, et al.
Publicado: (2023)

Bone Mineral Density Measurements and Association With Brain Structure and Cognitive Function: The Framingham Offspring Cohort
por: Stefanidou, Maria, et al.
Publicado: (2021)

Inter‐Relations of Orthostatic Blood Pressure Change, Aortic Stiffness, and Brain Structure and Function in Young Adults
por: Cooper, Leroy L., et al.
Publicado: (2017)

Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study
por: Spartano, Nicole L., et al.
Publicado: (2019)

Relation of plasma β‐amyloid, clusterin, and tau with cerebral microbleeds: Framingham Heart Study
por: Romero, José Rafael, et al.
Publicado: (2020)

Association of Metabolic Dysregulation With Volumetric Brain Magnetic Resonance Imaging and Cognitive Markers of Subclinical Brain Aging in Middle-Aged Adults: The Framingham Offspring Study
por: Tan, Zaldy S., et al.
Publicado: (2011)

The progression of carotid atherosclerosis and imaging markers of dementia
por: Baradaran, Hediyeh, et al.
Publicado: (2020)

Self-Reported Physical Activity and Relations to Growth and Neurotrophic Factors in Diabetes Mellitus: The Framingham Offspring Study
por: Spartano, Nicole L., et al.
Publicado: (2019)

Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle‐Aged Adults
por: Angoff, Rebecca, et al.
Publicado: (2022)

Red Blood Cell DHA Is Inversely Associated with Risk of Incident Alzheimer’s Disease and All-Cause Dementia: Framingham Offspring Study
por: Sala-Vila, Aleix, et al.
Publicado: (2022)

Associations between social relationship measures, serum brain-derived neurotrophic factor, and risk of stroke and dementia
por: Salinas, Joel, et al.
Publicado: (2017)

Accelerometer-determined physical activity and cognitive function in middle-aged and older adults from two generations of the Framingham Heart Study
por: Spartano, Nicole L., et al.
Publicado: (2019)

Overweight, Obesity, and Survival After Stroke in the Framingham Heart Study
por: Aparicio, Hugo J., et al.
Publicado: (2017)

Mid‐life and late‐life vascular risk factor burden and neuropathology in old age
por: Conner, Sarah C., et al.
Publicado: (2019)

Plasma clusterin levels and risk of dementia, Alzheimer's disease, and stroke
por: Weinstein, Galit, et al.
Publicado: (2016)

Cerebral small vessel disease burden is associated with decreased abundance of gut Barnesiella intestinihominis bacterium in the Framingham Heart Study
por: Fongang, Bernard, et al.
Publicado: (2023)

A population‐based meta‐analysis of circulating GFAP for cognition and dementia risk
por: Gonzales, Mitzi M., et al.
Publicado: (2022)

Aging, prevalence and risk factors of MRI-visible enlarged perivascular spaces
por: Lara, Frances Rodriguez, et al.
Publicado: (2022)

Whole genome sequence analyses of brain imaging measures in the Framingham Study
por: Sarnowski, Chloé, et al.
Publicado: (2018)

Association of Loneliness With 10-Year Dementia Risk and Early Markers of Vulnerability for Neurocognitive Decline
por: Salinas, Joel, et al.
Publicado: (2022)

Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study
por: Romero, José R., et al.
Publicado: (2016)

Relations of postural change in blood pressure with hypertension-mediated organ damage in middle-aged adults of the Framingham heart study: A cross-sectional study
por: Cooper, Leroy L., et al.
Publicado: (2022)

Association of Social Support With Brain Volume and Cognition
por: Salinas, Joel, et al.
Publicado: (2021)

Circulating biomarkers that predict incident dementia
por: Weinstein, Galit, et al.
Publicado: (2014)

Circulating Brain‐Derived Neurotrophic Factor Concentrations and the Risk of Cardiovascular Disease in the Community
por: Kaess, Bernhard M., et al.
Publicado: (2015)

MRI-Visible Perivascular Spaces and Risk of Incident Dementia: The Framingham Heart Study
por: Romero, Jose Rafael, et al.
Publicado: (2022)

Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer’s disease: Pooled analysis from 5 cohorts
por: Weinstein, Galit, et al.
Publicado: (2019)

The association of circulating endocannabinoids with neuroimaging and blood biomarkers of neuro-injury
por: Vered, Shiraz, et al.
Publicado: (2023)

ASSOCIATION OF COGNITION AND SMARTPHONE SURVEY ATTRIBUTES IN THE ELECTRONIC FRAMINGHAM HEART STUDY
por: Pathiravasan, Chathurangi, et al.
Publicado: (2022)

Whole blood microRNA expression associated with stroke: Results from the Framingham Heart Study
por: Salinas, Joel, et al.
Publicado: (2019)

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes
por: Vasan, Ramachandran S., et al.
Publicado: (2019)

Whole blood gene expression and white matter Hyperintensities
por: Lin, Honghuang, et al.
Publicado: (2017)

Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults
por: Pase, Matthew P., et al.
Publicado: (2023)

Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels
por: Sarnowski, Chloé, et al.
Publicado: (2022)

Menopause Status Moderates Sex Differences in Tau Burden: A Framingham PET Study
por: Buckley, Rachel F., et al.
Publicado: (2022)

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer’s disease: A prospective study in eight cohorts
por: Tynkkynen, Juho, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3vnc5i003lu7b5a9qo194rb829