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TFF3 interacts with LINGO2 to regulate EGFR activation for protection against colitis and gastrointestinal helminths

Intestinal epithelial cells (IEC) have important functions in nutrient absorption, barrier integrity, regeneration, pathogen-sensing, and mucus secretion. Goblet cells are a specialized cell type of IEC that secrete Trefoil factor 3 (TFF3) to regulate mucus viscosity and wound healing, but whether T...

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Detalles Bibliográficos
Autores principales: Belle, Nicole Maloney, Ji, Yingbiao, Herbine, Karl, Wei, Yun, Park, JoonHyung, Zullo, Kelly, Hung, Li-Yin, Srivatsa, Sriram, Young, Tanner, Oniskey, Taylor, Pastore, Christopher, Nieves, Wildaliz, Somsouk, Ma, Herbert, De’Broski R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764942/
https://www.ncbi.nlm.nih.gov/pubmed/31562318
http://dx.doi.org/10.1038/s41467-019-12315-1