A non-hierarchical organization of tumorigenic NG2 cells in glioblastoma promoted by EGFR

BACKGROUND: Expression of neuron-glial antigen 2 (NG2) identifies an aggressive malignant phenotype in glioblastoma (GBM). Mouse models have implicated NG2 in the genesis, evolution, and maintenance of glial cancers and have highlighted potential interactions between NG2 and epidermal growth factor...

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Detalles Bibliográficos
Autores principales: Al-Mayhani, Talal F, Heywood, Richard M, Vemireddy, Vamsidhara, Lathia, Justin D, Piccirillo, Sara G M, Watts, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765068/
https://www.ncbi.nlm.nih.gov/pubmed/30590711
http://dx.doi.org/10.1093/neuonc/noy204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765068/
https://www.ncbi.nlm.nih.gov/pubmed/30590711
http://dx.doi.org/10.1093/neuonc/noy204

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