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Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People

BACKGROUND: Cortisol is one of the important enzymes of saliva. Control of this hormone is an effective way to adjust the glucose level in diabetic patients. AIM: The aim of this research is to compare the salivary cortisol level in type 2 diabetic patients and pre-diabetics with healthy people. MET...

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Autores principales: Salehi, Maedeh, Mesgarani, Abbas, Karimipour, Soosan, Pasha, Shaghayegh Zahed, Kashi, Zahra, Abedian, Saeed, Mousazadeh, Mahmoud, Molania, Tahereh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765085/
https://www.ncbi.nlm.nih.gov/pubmed/31592281
http://dx.doi.org/10.3889/oamjms.2019.340
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author Salehi, Maedeh
Mesgarani, Abbas
Karimipour, Soosan
Pasha, Shaghayegh Zahed
Kashi, Zahra
Abedian, Saeed
Mousazadeh, Mahmoud
Molania, Tahereh
author_facet Salehi, Maedeh
Mesgarani, Abbas
Karimipour, Soosan
Pasha, Shaghayegh Zahed
Kashi, Zahra
Abedian, Saeed
Mousazadeh, Mahmoud
Molania, Tahereh
author_sort Salehi, Maedeh
collection PubMed
description BACKGROUND: Cortisol is one of the important enzymes of saliva. Control of this hormone is an effective way to adjust the glucose level in diabetic patients. AIM: The aim of this research is to compare the salivary cortisol level in type 2 diabetic patients and pre-diabetics with healthy people. METHODS: In this case-control study (2018), the unstimulated salivary samples were collected from 44 patients with type 2 diabetes, 44 pre-diabetic people (case group), and 44 healthy subjects (control group), matched for age and gender. The samples were transferred to the laboratory, and salivary cortisol level was measured using ELISA. Data were analysed using SPSS 22 and Chi 2 tests. RESULTS: The mean salivary cortisol level in type 2 diabetic patients was 3.14 ± 1.17, in pre-diabetic cases was 1.83 ± 0.68, and in healthy controls was 0.86 ± 0.43 (P < 0.001). The mean DMFT in type 2 diabetic patients was 19.6 ± 6.5, in the pre-diabetic group was 13.43 ± 4.5, and in healthy controls was 9.38 ± 3.72 (P < 0.001). CONCLUSION: With regards to the results, salivary cortisol level in type 2 diabetic patients is more than pre-diabetic people, and in pre-diabetic people is more than healthy people. Also, there was a significant relation between salivary cortisol level and DMFT index.
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spelling pubmed-67650852019-10-07 Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People Salehi, Maedeh Mesgarani, Abbas Karimipour, Soosan Pasha, Shaghayegh Zahed Kashi, Zahra Abedian, Saeed Mousazadeh, Mahmoud Molania, Tahereh Open Access Maced J Med Sci Dental Science BACKGROUND: Cortisol is one of the important enzymes of saliva. Control of this hormone is an effective way to adjust the glucose level in diabetic patients. AIM: The aim of this research is to compare the salivary cortisol level in type 2 diabetic patients and pre-diabetics with healthy people. METHODS: In this case-control study (2018), the unstimulated salivary samples were collected from 44 patients with type 2 diabetes, 44 pre-diabetic people (case group), and 44 healthy subjects (control group), matched for age and gender. The samples were transferred to the laboratory, and salivary cortisol level was measured using ELISA. Data were analysed using SPSS 22 and Chi 2 tests. RESULTS: The mean salivary cortisol level in type 2 diabetic patients was 3.14 ± 1.17, in pre-diabetic cases was 1.83 ± 0.68, and in healthy controls was 0.86 ± 0.43 (P < 0.001). The mean DMFT in type 2 diabetic patients was 19.6 ± 6.5, in the pre-diabetic group was 13.43 ± 4.5, and in healthy controls was 9.38 ± 3.72 (P < 0.001). CONCLUSION: With regards to the results, salivary cortisol level in type 2 diabetic patients is more than pre-diabetic people, and in pre-diabetic people is more than healthy people. Also, there was a significant relation between salivary cortisol level and DMFT index. Republic of Macedonia 2019-07-25 /pmc/articles/PMC6765085/ /pubmed/31592281 http://dx.doi.org/10.3889/oamjms.2019.340 Text en Copyright: © 2019 Maedeh Salehi, Abbas Mesgarani, Soosan Karimipour, Shaghayegh Zahed Pasha, Zahra Kashi, Saeed Abedian, Mahmoud Mousazadeh, Tahereh Molania. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Dental Science
Salehi, Maedeh
Mesgarani, Abbas
Karimipour, Soosan
Pasha, Shaghayegh Zahed
Kashi, Zahra
Abedian, Saeed
Mousazadeh, Mahmoud
Molania, Tahereh
Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People
title Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People
title_full Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People
title_fullStr Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People
title_full_unstemmed Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People
title_short Comparison of Salivary Cortisol Level in Type 2 Diabetic Patients and Pre-Diabetics with Healthy People
title_sort comparison of salivary cortisol level in type 2 diabetic patients and pre-diabetics with healthy people
topic Dental Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765085/
https://www.ncbi.nlm.nih.gov/pubmed/31592281
http://dx.doi.org/10.3889/oamjms.2019.340
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