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AT-dinucleotide rich sequences drive fragile site formation

Common fragile sites (CFSs) are genomic regions prone to breakage under replication stress conditions recurrently rearranged in cancer. Many CFSs are enriched with AT-dinucleotide rich sequences (AT-DRSs) which have the potential to form stable secondary structures upon unwinding the double helix du...

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Detalles Bibliográficos
Autores principales:	Irony-Tur Sinai, Michal, Salamon, Anita, Stanleigh, Noemie, Goldberg, Tchelet, Weiss, Aryeh, Wang, Yuh-Hwa, Kerem, Batsheva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765107/ https://www.ncbi.nlm.nih.gov/pubmed/31410468 http://dx.doi.org/10.1093/nar/gkz689

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