Enhancement of LacI binding in vivo

Transcription factors (TFs) bind to specific sequences in DNA to regulate transcription. Despite extensive measurements of TFs’ dissociation constant (K(d)) in vitro, their apparent K(d)in vivo are usually unknown. LacI, a bacterial TF, is often used to artificially recruit proteins onto eukaryotic...

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Detalles Bibliográficos
Autores principales: Du, Manyu, Kodner, Seth, Bai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765135/
https://www.ncbi.nlm.nih.gov/pubmed/31396617
http://dx.doi.org/10.1093/nar/gkz698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765135/
https://www.ncbi.nlm.nih.gov/pubmed/31396617
http://dx.doi.org/10.1093/nar/gkz698

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