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Enhancement of LacI binding in vivo
Transcription factors (TFs) bind to specific sequences in DNA to regulate transcription. Despite extensive measurements of TFs’ dissociation constant (K(d)) in vitro, their apparent K(d)in vivo are usually unknown. LacI, a bacterial TF, is often used to artificially recruit proteins onto eukaryotic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765135/ https://www.ncbi.nlm.nih.gov/pubmed/31396617 http://dx.doi.org/10.1093/nar/gkz698 |