A new mouse model of GLUT1 deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain

Dysfunction of glucose transporter 1 (GLUT1) proteins causes infantile epilepsy, which is designated as a GLUT1 deficiency syndrome (GLUT1DS; OMIM #606777). Patients with GLUT1DS display varied clinical phenotypes, such as infantile seizures, ataxia, severe mental retardation with learning disabilit...

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Detalles Bibliográficos
Autores principales: Furuse, Tamio, Mizuma, Hiroshi, Hirose, Yuuki, Kushida, Tomoko, Yamada, Ikuko, Miura, Ikuo, Masuya, Hiroshi, Funato, Hiromasa, Yanagisawa, Masashi, Onoe, Hirotaka, Wakana, Shigeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765196/
https://www.ncbi.nlm.nih.gov/pubmed/31399478
http://dx.doi.org/10.1242/dmm.038828

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