Cargando…

Regulation of La/SSB-dependent viral gene expression by pre-tRNA 3′ trailer-derived tRNA fragments

tRNA-derived RNA fragments (tRFs) have emerged as a new class of functional RNAs implicated in cancer, metabolic and neurological disorders, and viral infection. Yet our understanding of their biogenesis and functions remains limited. In the present study, through analysis of small RNA profile we ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cho, Hee, Lee, Wooseong, Kim, Geon-Woo, Lee, Seung-Hoon, Moon, Jae-Su, Kim, Minwoo, Kim, Hyun Seok, Oh, Jong-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765225/ https://www.ncbi.nlm.nih.gov/pubmed/31504775 http://dx.doi.org/10.1093/nar/gkz732

Ejemplares similares

Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNA(Asn), tRNA(Gln), tRNA(Glu) and tRNA(Pro)
por: Jia, Zidong, et al.
Publicado: (2022)

Processing by RNase 1 forms tRNA halves and distinct Y RNA fragments in the extracellular environment
por: Nechooshtan, Gal, et al.
Publicado: (2020)

Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator
por: Krutyhołowa, Rościsław, et al.
Publicado: (2019)

Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis
por: Megel, Cyrille, et al.
Publicado: (2019)

Dynamics of intracellular stress-induced tRNA trafficking
por: Dhakal, Rabin, et al.
Publicado: (2019)

Endogenous piRNA-guided slicing triggers responder and trailer piRNA production from viral RNA in Aedes aegypti mosquitoes
por: Joosten, Joep, et al.
Publicado: (2021)

GNAT toxins evolve toward narrow tRNA target specificities
por: Bikmetov, Dmitry, et al.
Publicado: (2022)

Hierarchical groove discrimination by Class I and II aminoacyl-tRNA synthetases reveals a palimpsest of the operational RNA code in the tRNA acceptor-stem bases
por: Carter, Charles W, et al.
Publicado: (2018)

The RNA chaperone La promotes pre-tRNA maturation via indiscriminate binding of both native and misfolded targets
por: Vakiloroayaei, Ana, et al.
Publicado: (2017)

Sustenance of Escherichia coli on a single tRNA(Met)
por: Govindan, Ashwin, et al.
Publicado: (2018)

Identification of a novel tRNA wobble uridine modifying activity in the biosynthesis of 5-methoxyuridine
por: Ryu, Huijeong, et al.
Publicado: (2018)

Pseudouridine-mediated translation control of mRNA by methionine aminoacyl tRNA synthetase
por: Levi, Ofri, et al.
Publicado: (2020)

Dicer dependent tRNA derived small RNAs promote nascent RNA silencing
por: Di Fazio, Arianna, et al.
Publicado: (2022)

Impact of intron removal from tRNA genes on Saccharomyces cerevisiae
por: Hayashi, Sachiko, et al.
Publicado: (2019)

A deafness-associated tRNA mutation caused pleiotropic effects on the m(1)G37 modification, processing, stability and aminoacylation of tRNA(Ile) and mitochondrial translation
por: Meng, Feilong, et al.
Publicado: (2021)

Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery
por: Liu, Ze, et al.
Publicado: (2023)

Twice exploration of tRNA +1 frameshifting in an elongation cycle of protein synthesis
por: Gamper, Howard, et al.
Publicado: (2021)

Three tRNA nuclear exporters in S. cerevisiae: parallel pathways, preferences, and precision
por: Chatterjee, Kunal, et al.
Publicado: (2022)

tRNA 3′ shortening by LCCR4 as a response to stress in Trypanosoma brucei
por: Cristodero, Marina, et al.
Publicado: (2021)

Eukaryotic tRNA sequences present conserved and amino acid-specific structural signatures
por: Westhof, Eric, et al.
Publicado: (2022)

The MRPP1/MRPP2 complex is a tRNA-maturation platform in human mitochondria
por: Reinhard, Linda, et al.
Publicado: (2017)

Correlation between equi-partition of aminoacyl-tRNA synthetases and amino-acid biosynthesis pathways
por: Takénaka, Akio, et al.
Publicado: (2020)

Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs
por: Chen, Zhuojia, et al.
Publicado: (2019)

Charcot–Marie–Tooth mutation in glycyl-tRNA synthetase stalls ribosomes in a pre-accommodation state and activates integrated stress response
por: Mendonsa, Samantha, et al.
Publicado: (2021)

Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism
por: Chen, Danni, et al.
Publicado: (2019)

The hyperthermophilic partners Nanoarchaeum and Ignicoccus stabilize their tRNA T-loops via different but structurally equivalent modifications
por: Rose, Simon, et al.
Publicado: (2020)

Evolutionary repair reveals an unexpected role of the tRNA modification m(1)G37 in aminoacylation
por: Clifton, Ben E, et al.
Publicado: (2021)

A tRNA modifying enzyme as a tunable regulatory nexus for bacterial stress responses and virulence
por: Fleming, Brittany A, et al.
Publicado: (2022)

Translation initiation with exotic amino acids using EF-P-responsive artificial initiator tRNA
por: Katoh, Takayuki, et al.
Publicado: (2023)

Structural basis of tRNA(Pro) acceptor stem recognition by a bacterial trans-editing domain
por: Ma, Xiao, et al.
Publicado: (2023)

Codon-specific effects of tRNA anticodon loop modifications on translational misreading errors in the yeast Saccharomyces cerevisiae
por: Joshi, Kartikeya, et al.
Publicado: (2018)

A coronary artery disease-associated tRNA(Thr) mutation altered mitochondrial function, apoptosis and angiogenesis
por: Jia, Zidong, et al.
Publicado: (2019)

FARS2 deficiency in Drosophila reveals the developmental delay and seizure manifested by aberrant mitochondrial tRNA metabolism
por: Fan, Wenlu, et al.
Publicado: (2021)

A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism
por: Meng, Feilong, et al.
Publicado: (2022)

A new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing
por: Chen, Ximing, et al.
Publicado: (2022)

Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase
por: de Potter, Bastiaan, et al.
Publicado: (2023)

Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB
por: Hensen, Fenna, et al.
Publicado: (2019)

Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function
por: Zhang, Qinghai, et al.
Publicado: (2018)

Position 34 of tRNA is a discriminative element for m(5)C38 modification by human DNMT2
por: Huang, Zhi-Xuan, et al.
Publicado: (2021)

A homozygous mutation in the human selenocysteine tRNA gene impairs UGA recoding activity and selenoproteome regulation by selenium
por: Vindry, Caroline, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o94hndrpv54ekeuupboacvnpjd