Cargando…
The single-cell transcriptomic landscape of early human diabetic nephropathy
Diabetic nephropathy is characterized by damage to both the glomerulus and tubulointerstitium, but relatively little is known about accompanying cell-specific changes in gene expression. We performed unbiased single-nucleus RNA sequencing (snRNA-seq) on cryopreserved human diabetic kidney samples to...
Autores principales: | Wilson, Parker C., Wu, Haojia, Kirita, Yuhei, Uchimura, Kohei, Ledru, Nicolas, Rennke, Helmut G., Welling, Paul A., Waikar, Sushrut S., Humphreys, Benjamin D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765272/ https://www.ncbi.nlm.nih.gov/pubmed/31506348 http://dx.doi.org/10.1073/pnas.1908706116 |
Ejemplares similares
-
Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury
por: Kirita, Yuhei, et al.
Publicado: (2020) -
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
por: Muto, Yoshiharu, et al.
Publicado: (2021) -
A single-cell multiomic analysis of kidney organoid differentiation
por: Yoshimura, Yasuhiro, et al.
Publicado: (2023) -
Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression
por: Wilson, Parker C., et al.
Publicado: (2022) -
Chromogranin A Tubulopathy: Differing Histopathologic Patterns of Acute Tubular Injury in the Setting of Neuroendocrine Neoplasms
por: Sekulic, Miroslav, et al.
Publicado: (2019)