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Simultaneous profiling of 3D genome structure and DNA methylation in single human cells
Dynamic 3D chromatin conformation is a critical mechanism for gene regulation during development and disease. Despite this, profiling of 3D genome structure from complex tissues with cell-type specific resolution remains challenging. Recent efforts have demonstrated that cell-type specific epigenomi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765423/ https://www.ncbi.nlm.nih.gov/pubmed/31501549 http://dx.doi.org/10.1038/s41592-019-0547-z |