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Simultaneous profiling of 3D genome structure and DNA methylation in single human cells

Dynamic 3D chromatin conformation is a critical mechanism for gene regulation during development and disease. Despite this, profiling of 3D genome structure from complex tissues with cell-type specific resolution remains challenging. Recent efforts have demonstrated that cell-type specific epigenomi...

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Detalles Bibliográficos
Autores principales: Lee, Dong-Sung, Luo, Chongyuan, Zhou, Jingtian, Chandran, Sahaana, Rivkin, Angeline, Bartlett, Anna, Nery, Joseph R., Fitzpatrick, Conor, O’Connor, Carolyn, Dixon, Jesse R., Ecker, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6765423/
https://www.ncbi.nlm.nih.gov/pubmed/31501549
http://dx.doi.org/10.1038/s41592-019-0547-z