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Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin

Primary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localizati...

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Detalles Bibliográficos
Autores principales: Meconi, Federico, Secchi, Roberto, Palmieri, Raffaele, Vaccarini, Sara, Rapisarda, Vito Mario, Giannì, Laura, Esposito, Fabiana, Provenzano, Ida, Nasso, Daniela, Pupo, Livio, Cantonetti, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766127/
https://www.ncbi.nlm.nih.gov/pubmed/31637066
http://dx.doi.org/10.1155/2019/9651207
Descripción
Sumario:Primary cutaneous anaplastic large cell lymphoma is a CD-30 positive lymphoproliferative disorder with good prognosis, usually treated with radiation therapy and surgery. Head, neck, and extremities are the most frequently involved sites. In this paper, we describe an unusual case of oral localization, recurring after skin-involving radiotherapy, successfully treated with sixteen cycles of brentuximab vedotin. This could be a more effective approach with a less detrimental toll for treating these rare disorders.