miR-199a-5p Represses Protective Autophagy and Overcomes Chemoresistance by Directly Targeting DRAM1 in Acute Myeloid Leukemia

Chemotherapy resistance is still a primary clinical obstacle to the successful treatment of acute myeloid leukemia (AML). The underlying mechanisms of drug resistance are complicated and have not been fully understood. Here, we found that miR-199a-5p levels were significantly reduced in refractory/r...

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Detalles Bibliográficos
Autores principales: Li, Yang, Zhang, Guojun, Wu, Bin, Yang, Wei, Liu, Zhuogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766143/
https://www.ncbi.nlm.nih.gov/pubmed/31636666
http://dx.doi.org/10.1155/2019/5613417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766143/
https://www.ncbi.nlm.nih.gov/pubmed/31636666
http://dx.doi.org/10.1155/2019/5613417

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