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miR-199a-5p Represses Protective Autophagy and Overcomes Chemoresistance by Directly Targeting DRAM1 in Acute Myeloid Leukemia
Chemotherapy resistance is still a primary clinical obstacle to the successful treatment of acute myeloid leukemia (AML). The underlying mechanisms of drug resistance are complicated and have not been fully understood. Here, we found that miR-199a-5p levels were significantly reduced in refractory/r...
Autores principales: | Li, Yang, Zhang, Guojun, Wu, Bin, Yang, Wei, Liu, Zhuogang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766143/ https://www.ncbi.nlm.nih.gov/pubmed/31636666 http://dx.doi.org/10.1155/2019/5613417 |
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