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Nuclear receptor subfamily 4 group A member 2 inhibits activation of ERK signaling and cell growth in response to β-adrenergic stimulation in adult rat cardiomyocytes

Sustained elevation of sympathetic activity is an important contributor to pathological cardiac hypertrophy, ventricular arrhythmias, and left ventricular contractile dysfunction in chronic heart failure. The orphan nuclear receptor NR4A2 is an immediate early-response gene activated in the heart un...

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Detalles Bibliográficos
Autores principales: Ashraf, Sadia, Hegazy, Yassmin K., Harmancey, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766613/
https://www.ncbi.nlm.nih.gov/pubmed/31188636
http://dx.doi.org/10.1152/ajpcell.00526.2018