Cargando…
Nuclear receptor subfamily 4 group A member 2 inhibits activation of ERK signaling and cell growth in response to β-adrenergic stimulation in adult rat cardiomyocytes
Sustained elevation of sympathetic activity is an important contributor to pathological cardiac hypertrophy, ventricular arrhythmias, and left ventricular contractile dysfunction in chronic heart failure. The orphan nuclear receptor NR4A2 is an immediate early-response gene activated in the heart un...
Autores principales: | Ashraf, Sadia, Hegazy, Yassmin K., Harmancey, Romain |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766613/ https://www.ncbi.nlm.nih.gov/pubmed/31188636 http://dx.doi.org/10.1152/ajpcell.00526.2018 |
Ejemplares similares
-
Crosstalk between beta‐adrenergic and insulin signaling mediates mechanistic target of rapamycin hyperactivation in liver of high‐fat diet‐fed male mice
por: Ashraf, Sadia, et al.
Publicado: (2021) -
Prolonged cardiac NR4A2 activation causes dilated cardiomyopathy in mice
por: Ashraf, Sadia, et al.
Publicado: (2022) -
UCP3 (Uncoupling Protein 3) Insufficiency Exacerbates Left Ventricular Diastolic Dysfunction During Angiotensin II‐Induced Hypertension
por: Chen, Xu, et al.
Publicado: (2021) -
ACE-inhibition, but not weight reduction restores cardiomyocyte response to β-adrenergic stimulation in the metabolic syndrome
por: Nevelsteen, Ines, et al.
Publicado: (2013) -
Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes
por: Bathe-Peters, Marc, et al.
Publicado: (2021)