AhR–ROR-γt complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus

The cytokine IL-17A plays critical roles in the pathogenesis of autoimmune diseases. The frequencies of MAP kinase kinase kinase kinase 3 [also named germinal center kinase–like kinase (GLK)]-overexpressing T cells are correlated with disease severity of systemic lupus erythematosus (SLE). T-cell–sp...

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Detalles Bibliográficos
Autores principales: Chuang, Huai-Chia, Chen, Yi-Ming, Chen, Ming-Han, Hung, Wei-Ting, Yang, Huang-Yu, Tseng, Yang-Hao, Tan, Tse-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766655/
https://www.ncbi.nlm.nih.gov/pubmed/31318609
http://dx.doi.org/10.1096/fj.201900105RR

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