Cargando…

Mesenchymal Stromal Cells Modulate Corneal Alloimmunity via Secretion of Hepatocyte Growth Factor

Mesenchymal stromal cells (MSCs) are multipotent stem cells that participate in tissue repair and possess considerable immunomodulatory potential. MSCs have been shown to promote allograft survival, yet the mechanisms behind this phenomenon have not been fully defined. Here, we investigate the capac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mittal, Sharad K., Foulsham, William, Shukla, Sachin, Elbasiony, Elsayed, Omoto, Masahiro, Chauhan, Sunil K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Cell‐Based Drug Development, Screening, and Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766689/ https://www.ncbi.nlm.nih.gov/pubmed/31179638 http://dx.doi.org/10.1002/sctm.19-0004

Ejemplares similares

Mesenchymal Stromal Cells Suppress T-Cell-Mediated Delayed-Type Hypersensitivity via ALCAM-CD6 Interaction
por: Cho, WonKyung J, et al.
Publicado: (2023)

Treatment of chronic GvHD with mesenchymal stromal cells induces durable responses: A phase II study
por: Boberg, Erik, et al.
Publicado: (2020)

miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats
por: Cui, Chengcheng, et al.
Publicado: (2016)

Cytokine Mixtures Mimicking the Local Milieu in Patients with Inflammatory Bowel Disease Impact Phenotype and Function of Mesenchymal Stromal Cells
por: Barnhoorn, Marieke C, et al.
Publicado: (2022)

Stromal cells from perinatal and adult sources modulate the inflammatory immune response in vitro by decreasing Th1 cell proliferation and cytokine secretion
por: Khoury, Oula, et al.
Publicado: (2019)

Suppression of lipopolysaccharide-induced corneal opacity by hepatocyte growth factor
por: Elbasiony, Elsayed, et al.
Publicado: (2022)

Mesenchymal Stem Cell-derived Extracellular Vesicles Prevent Experimental Bronchopulmonary Dysplasia Complicated By Pulmonary Hypertension
por: Sharma, Mayank, et al.
Publicado: (2022)

Systemic multipotent adult progenitor cells protect the cerebellum after asphyxia in fetal sheep
por: Gussenhoven, Ruth, et al.
Publicado: (2020)

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress
por: Thorne, Natasha, et al.
Publicado: (2016)

Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A
por: Long, Yan, et al.
Publicado: (2016)

Human Mesenchymal Stem Cells Impact Th17 and Th1 Responses Through a Prostaglandin E2 and Myeloid-Dependent Mechanism
por: Rozenberg, Ayal, et al.
Publicado: (2016)

Concise Review: Therapeutic Potential of the Mesenchymal Stem Cell Derived Secretome and Extracellular Vesicles for Radiation‐Induced Lung Injury: Progress and Hypotheses
por: Xu, Siguang, et al.
Publicado: (2019)

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae
por: Perlee, Desiree, et al.
Publicado: (2019)

A Phase I Study to Assess the Safety and Cancer‐Homing Ability of Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer
por: Schweizer, Michael T., et al.
Publicado: (2019)

Phenotypic Drug Screening for Dysferlinopathy Using Patient‐Derived Induced Pluripotent Stem Cells
por: Kokubu, Yuko, et al.
Publicado: (2019)

Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach
por: Drowley, Lauren, et al.
Publicado: (2019)

Chemotherapy‐Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood
por: Vojnits, Kinga, et al.
Publicado: (2019)

Brain‐derived neurotropic factor mediates neuroprotection of mesenchymal stem cell‐derived extracellular vesicles against severe intraventricular hemorrhage in newborn rats
por: Ahn, So Yoon, et al.
Publicado: (2020)

Lithium modulates miR‐1906 levels of mesenchymal stem cell‐derived extracellular vesicles contributing to poststroke neuroprotection by toll‐like receptor 4 regulation
por: Haupt, Matteo, et al.
Publicado: (2020)

Drug screening platform using human induced pluripotent stem cell‐derived atrial cardiomyocytes and optical mapping
por: Gunawan, Marvin G., et al.
Publicado: (2020)

Rabbit neurospheres as a novel in vitro tool for studying neurodevelopmental effects induced by intrauterine growth restriction
por: Barenys, Marta, et al.
Publicado: (2020)

Allogeneic Cell Combination Therapy Ameliorates Chronic Kidney Disease-Induced Heart Failure with Preserved Ejection Fraction
por: Rieger, Angela C, et al.
Publicado: (2022)

Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina
por: Dorgau, Birthe, et al.
Publicado: (2022)

Site-Specific Integration of TRAIL in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy
por: Wang, Zujia, et al.
Publicado: (2022)

Otic Organoids Containing Spiral Ganglion Neuron-like Cells Derived from Human-induced Pluripotent Stem Cells as a Model of Drug-induced Neuropathy
por: Kurihara, Sho, et al.
Publicado: (2022)

Generation of Human Nociceptor-Enriched Sensory Neurons for the Study of Pain-Related Dysfunctions
por: Holzer, Anna-Katharina, et al.
Publicado: (2022)

Metabolic Maturation Increases Susceptibility to Hypoxia-induced Damage in Human iPSC-derived Cardiomyocytes
por: Peters, Marijn C, et al.
Publicado: (2022)

Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy
por: Golubeva, Diana, et al.
Publicado: (2023)

Increased activity of lacrimal gland mast cells are associated with corneal epitheliopathy in aged mice
por: Elbasiony, Elsayed, et al.
Publicado: (2023)

Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands
por: Conole, Daniel, et al.
Publicado: (2018)

The Cardiovascular Effects of a Meal: J‐T(peak) and T(peak)‐T(end) Assessment and Further Insights Into the Physiological Effects
por: Täubel, Jörg, et al.
Publicado: (2019)

The purinergic receptor antagonist oxidized adenosine triphosphate suppresses immune-mediated corneal allograft rejection
por: Foulsham, William, et al.
Publicado: (2019)

Personalized medicine: Striding from genes to medicines
por: Nair, Sunita R.
Publicado: (2010)

Diabetes mellitus: Exploring the challenges in the drug development process
por: Vaz, Julius A., et al.
Publicado: (2012)

Evaluation of a Scenario in Which Estimates of Bioequivalence Are Biased and a Proposed Solution: t(last) (Common)
por: Fisher, Dennis, et al.
Publicado: (2015)

Effect of Study Design on Sample Size in Studies Intended to Evaluate Bioequivalence of Inhaled Short‐Acting β‐Agonist Formulations
por: Zeng, Yaohui, et al.
Publicado: (2017)

Thorough QT/QTc Evaluation of the Cardiac Safety of Secnidazole at Therapeutic and Supratherapeutic Doses in Healthy Individuals
por: Darpo, Borje, et al.
Publicado: (2017)

Estimation of the Power of the Food Effect on QTc to Show Assay Sensitivity
por: Ferber, Georg, et al.
Publicado: (2017)

Model‐Based Evaluation of Exenatide Effects on the QT Interval in Healthy Subjects Following Continuous IV Infusion
por: Cirincione, Brenda, et al.
Publicado: (2017)

Influence of Meals and Glycemic Changes on QT Interval Dynamics
por: Cirincione, Brenda, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_i707f7a0nf6heis6ad8tnp9j1d